A case of cerebral thromboembolism in ulcerative colitis.
- Author:
Jong Taek OH
1
;
Seong Woo JEON
;
Eung Kap LEE
;
Soon Hak LEE
;
Min Kyu JUNG
;
Sung Kook KIM
Author Information
1. Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea. swjeon@knu.ac.kr
- Publication Type:Case Report
- Keywords:
Ulcerative colitis;
Cerebral infarction;
Thromboembolism
- MeSH:
Abdominal Pain;
Adult;
Angiography;
Cause of Death;
Cerebral Infarction;
Colitis, Ulcerative;
Diarrhea;
Factor V;
Hemiplegia;
Humans;
Infarction;
Magnetic Resonance Imaging;
Middle Cerebral Artery;
Nausea;
Neck;
Platelet Aggregation Inhibitors;
Protein S;
Thromboembolism;
Ulcer;
Vertebral Artery;
Vomiting
- From:Korean Journal of Medicine
2009;77(4):498-502
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Although cerebral thromboembolic disease is a rare extraintestinal manifestation of ulcerative colitis, it is one of the major causes of death in patients with the disease. A 29-year-old man who had a 7-year history of ulcerative colitis was admitted to our hospital complaining of nausea, vomiting, bloody diarrhea, and colicky abdominal pain. Fourteen days after admission, he developed sudden-onset left pure motor hemiplegia. Magnetic resonance imaging and angiography revealed an infarction involving the right temporo-occipital hemisphere and diffuse middle cerebral artery territory. Neck computed tomography angiography showed no evidence of cervical carotid or vertebral artery abnormalities, and transthoracic and transesophageal echocardiograms revealed no evidence of thrombi. Factor V was elevated to 176% (normal 50~150%) and protein S antigen had decreased to 57% (normal 60~150%). He was managed with antiplatelet agents and a total proctocolectomy.
