Nausea and Vomiting in Pregnancy.
- Author:
Kyeong Ok KIM
1
Author Information
1. Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea. cello7727@naver.com
- Publication Type:Review
- Keywords:
Nausea and vomiting, pregnancy;
Hyperemesis gravidarum;
Therapy
- MeSH:
Dehydration;
Doxylamine;
Female;
Fetus;
Humans;
Hyperemesis Gravidarum;
Liver;
Mothers;
Nausea;
Precipitating Factors;
Pregnancy;
Pyridoxine;
Serotonin;
Succinic Acid;
Thiamine;
Vomiting
- From:Korean Journal of Medicine
2012;82(5):525-531
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Nausea and vomiting in pregnancy (NVP) is common medical condition during pregnancy and associated with hormonal change. Early recognition and active treatment is warranted because it can be associated with adverse healthy effect in both fetus and mother. First, the possibility of other gastrointestinal disorder should be considered and precipitating factor, renal and liver function should be evaluated. Primay recommended pharmacotherapy is the combination of oral pyridoxine hydrochloride and doxylamine succinate. Other options including dopamin (D2) receptor antagonist, antihistamine and serotonine 5 hydroxytryptamine 3-receptor (5-HT3) can be used. Fluid mixed with multivitamine including thiamine supplement should be considered in case of severe dehydration and hyperemesis gravidarum. Emotional support is also an important part in the management of NVP. The physician shoud apply individualized approach for the safest and most appripriate treatment.
