Management of Chemotherapy Induced Nausea and Vomiting.
- Author:
Kyung Ho SONG
1
Author Information
1. Division of Gastroenterology and Hepatology, Department of Internal Medicine, Konyang University Hospital, Daejeon, Korea. postit@kyuh.ac.kr
- Publication Type:Review
- Keywords:
Antiemetics;
Chemotherapy
- MeSH:
Antiemetics;
Nausea;
Serotonin 5-HT3 Receptor Antagonists;
Vomiting
- From:Korean Journal of Medicine
2012;82(5):532-536
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Chemotherapy induced nausea and vomiting (CINV) is typically biphasic. The acute phase usually peaks in 5-6 hours after the administration of chemotherapeutic agents and the delayed phase can occur subsequently over 24hours after chemotherapy. Antiemetic therapy is crucial to prevent this unwanted side effect effectively, and NK1 antagonist, 5-HT3 antagonist, corticosteroid are the main player. The combination and dosing is determined by the emetogenicity of the chemotherapeutic agents to be administrated.
