Cerebral sinovenous thrombosis associated with nephrotic syndrome.
- Author:
Hyun Jung KIM
1
;
Duk Eun JUNG
;
Seung Jae BYUN
;
Yu Min LEE
;
Ji Eun LEE
;
Seon Ho AHN
;
Ju Hung SONG
Author Information
1. Department of Internal Medicine, Wonkwang University School of Medicine, Iksan, Korea. ashneph@wonkwang.ac.kr
- Publication Type:Case Report
- Keywords:
Cerebral thrombosis;
Nephrotic syndrome
- MeSH:
Anticoagulants;
Brain;
Early Diagnosis;
Edema;
Headache;
Humans;
Hyperlipidemias;
Hypoalbuminemia;
Intracranial Thrombosis;
Magnetic Resonance Imaging;
Nausea;
Nephrosis, Lipoid;
Nephrotic Syndrome;
Proteinuria;
Renal Veins;
Thrombosis;
Venous Thrombosis;
Young Adult
- From:Korean Journal of Medicine
2009;77(4):517-521
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Nephrotic syndrome is associated with proteinuria, hypoalbuminemia, edema, hyperlipidemia, and thromboembolic complications. Thromboembolic complications of nephrotic syndrome are common, especially in the renal vein, while cerebral venous thrombosis is a less frequent complication of minimal change nephrotic syndrome. The pathophysiology remains unclear, but various changes in coagulant and anticoagulant factors may be responsible. We report a case of cerebral venous thrombosis associated with nephrotic syndrome. A 19-year-old man was admitted with a headache and nausea. Cerebral thrombosis was diagnosed on brain computed tomography and magnetic resonance imaging. He recovered gradually after treatment with anticoagulants and achieved control of the nephrotic syndrome. A discussion of this case, coupled with a review of the literature, emphasizes that an early diagnosis is essential for anticoagulation therapy and a successful outcome.
