Spinocerebellar Ataxia Type 2 with Only Clinical Feature of Memory Impairment: Case Report.
10.12779/dnd.2014.13.1.16
- Author:
Jaejeong JOO
1
;
Sang Wo HAN
;
Sang Won HA
;
Jeong Ho HAN
;
Doo Eung KIM
;
Youngsoon YANG
Author Information
1. Department of Neurology, SVH Medical Center, Seoul, Korea. astro76@naver.com
- Publication Type:Case Report
- Keywords:
Spinocerebellar ataxia type 2;
Memory impairment
- MeSH:
Ataxia;
Cerebellar Ataxia;
Chorea;
Dysarthria;
Eye Movements;
Female;
Gait;
Gait Ataxia;
Hand;
Humans;
Memory*;
Memory, Short-Term;
Middle Aged;
Ophthalmoplegia;
Saccades;
Spinocerebellar Ataxias*
- From:Dementia and Neurocognitive Disorders
2014;13(1):16-19
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Spinocerebellar ataxia (SCA) is one of a group of genetic disorders characterized by slowly progressive incoordination of gait and often associated with poor coordination of hands, speech, and eye movements. There are more than 35 different types of spinocerebellar ataxias, each caused by a different genetic mutation. Spinocerebellar ataxia type 2 (SCA2) is a subtype of type I autosomal dominant cerebellar ataxia (ADCA type I) characterized by truncal ataxia, dysarthria, slowed saccades and less commonly ophthalmoparesis and chorea. The age at onset varies from 3 to 79 years (mean 33). Usually, the first symptom of the disease is the gait ataxia, followed by the cerebellar dysarthria. Of late, other clinical manifestations of SCA2 are the cognitive dysfunctions, which include frontal executive impairment, verbal short-term memory deficits as well as reduction of attention and concentration. We report a 56-year old woman identified as spinocerebellar ataxia type 2 (SCA2) with only clinical feature of memory impairment.
