The components of the proliferative membranes in retinopathy of prematurity: an electron microscopic study.
- Author:
Kyung In WOO
1
;
Sang In KWAK
;
Young Suk YU
Author Information
- Publication Type:Case Reports
- Keywords: electron microscopy; proliferative membrane; retinopathy of prematurity
- MeSH: Cataract Extraction; Child, Preschool; Gestational Age; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Microscopy, Electron; Retina/*ultrastructure; Retinopathy of Prematurity/*pathology
- From:Korean Journal of Ophthalmology 1992;6(1):36-43
- CountryRepublic of Korea
- Language:English
- Abstract: Electron microscopic examination of proliferative membranes in retinopathy of prematurity (ROP) was performed in order to evaluate the components of the membranes. The proliferative membranes were obtained from nine patients with ROP stage 5 during pars plicata lensectomy, vitrectomy, and delamination of membrane. Fibrous astrocytes, myofibroblasts, lymphocytes, macrophages, and calcification were found respectively in two cases, and fibroblast-like cells were found in one case. Varying amounts of collagen tissues were found in eight cases and vascular tissues in four cases. Most of membranes were hypocellular and composed mainly of collagen matrix. It is considered that fibrous astrocytes, myofibroblasts, fibroblasts, and vascular structures are involved in the formation of proliferative membranes of ROP, and that later these cells degenerate and disappear, and that finally only collagen matrix remains in the membranes.
