Concomitant Splenectomy during Hepatectomy in Patients with Liver Cirrhosis and Thrombocytopenia.
- Author:
Myung Ha SHIN
1
;
Yang Soo LIM
;
Yoon Jin HWANG
;
Yang Il KIM
Author Information
1. Department of Surgery, Biomolecular Engineering Center, Kyung- pook National University College of Medicine, Daegu, Korea. blackroseor@dreamwiz.com
- Publication Type:Original Article
- Keywords:
Concomitant splenectomy;
Liver cirrhosis;
Thrombocytopenia
- MeSH:
Bilirubin;
Blood Transfusion;
Carcinoma, Hepatocellular;
Hepatectomy*;
Humans;
Liver Cirrhosis*;
Liver*;
Platelet Count;
Retrospective Studies;
Splenectomy*;
Thrombocytopenia*
- From:Korean Journal of Hepato-Biliary-Pancreatic Surgery
2002;6(2):117-122
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: Resection of hepatocellular carcinoma in patients with liver cirrhosis and thrombocytopenia is risky. The benefit of concomitant splenectomy in cirrhotic patients is controversial. METHODS: To evaluate the efficacy of concomitant splenectomy in patients with liver cirrhosis and thrombocytopenia, 13 cirrhotic patients with thrombocytopenia (platelet count< or =80,000/mm3) were divided by two groups (Group I: the patients without concomitant splenectomy during hepatectomy, Group II: the patients with concomitant splenectomy). Intraoperative and postoperative parameters were retrospectively reviewed. RESULTS: Group II patients needed less amount of postoperative blood transfusion (Group I: 178.3+/-150 ml PRC in 3 patients, Group II: 107.1+/-100 ml in 2 patients, p=0.012, p= 0.041) and the platelet count was elevated to above 250,000/mm3 (p=0.003) and showed lower serum bilirubin level (p=0.037) within 1 week of operation in group II patients. CONCLUSION: The concomitant splenectomy during in patients of liver cirrhosis with thrombocytopenia may improve liver function and elevate platelet count.
