Mucoepidermoid Carcinoma of the Liver Diagnosed as Liver Abscess.
- Author:
Dongho CHOI
1
;
Kyeong Geun LEE
;
Han Joon KIM
;
Oh Jung KWON
;
Chan Kum PARK
;
Kwang Soo LEE
Author Information
1. Department of Surgery, College of Medicine, Hanyang University, Seoul, Korea. kslee@hanyang.ac.kr
- Publication Type:Case Report
- Keywords:
Mucoepidermoid carcinoma;
Liver;
Abscess
- MeSH:
Abscess;
Aged;
Alcian Blue;
Bile Ducts, Intrahepatic;
Carcinoma, Mucoepidermoid*;
Catheters;
Cholangiocarcinoma;
Cytoplasm;
Diagnosis;
Diaphragm;
Female;
Fever;
Flank Pain;
Hepatectomy;
Humans;
Intermediate Filaments;
Keratin-7;
Liver Abscess*;
Liver*;
Mucins
- From:Korean Journal of Hepato-Biliary-Pancreatic Surgery
2002;6(2):200-203
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Mucoepidermoid carcinoma of the liver is a rare variant of cholangiocarcinoma which contains both mucus-secreting glandular cells and squamous cells mixed in nests. We diagnosed a case of mucoepidermoid carcinoma of the liver in a 69-year-old woman who visited hospital because of fever, chill, right flank pain for one week. On admission, she was not jaundiced. Under a provisional diagnosis of liver abscess, a pigtail catheter was inserted to the abscess cavity. One month after the admission, despite conservative treatment, the abscess cavity remained. For a curative treatment and possible hiden malignancy, right hepatectomy of the liver and excision of partial diaphragm were done. Microscopically, the tumor mass composed of solid and invasive nests of epidermoid and mucin-producing cells with desmoplastic stroma. Alcian blue, Periodic-Acid Schiff (PAS) stainings confirmed the presence of mucin in the cytoplasm of mucus-secreting cells. Electron micrographs showed the presence of tonofilaments and confirmed the squamous nature of the tumor cells. The tumor cells, intrahepatic bile ducts and ductules were consistently reactive with cytokeratin 7. Adjacent nonneoplastic liver cells were negative to cytokeratin 7. In the present case, the tumor was diagnosed as mucoepidermoid carcinoma, which was arisen from the intrahepatic bile duct.
