Kimura's Disease Involving The Eyelid and Orbit.
- Author:
Do Hyun CHUNG
1
;
Byung Jin KIM
;
Yoon Duck KIM
Author Information
1. Department of Ophthalmology, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, Korea. ydkim@smc.samsung.co.kr
- Publication Type:Original Article
- Keywords:
Eosinophilia;
Eyelid swelling;
Kimura's disease;
Painless nodule;
Ptosis
- MeSH:
Adolescent;
Angiolymphoid Hyperplasia with Eosinophilia;
Arm;
Capillaries;
Diagnosis, Differential;
Eosinophilia;
Eosinophils;
Eyelids*;
Fibrosis;
Head;
Humans;
Korea;
Lymphocytes;
Magnetic Resonance Imaging;
Male;
Neck;
Orbit*
- From:Journal of the Korean Ophthalmological Society
2002;43(9):1789-1796
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Kimura's disease is a benign slow-growing subcutaneous tumor, which is manifested clinically by one or more inflammatory nodules invading mainly the head and neck. Orbital, eyelid and lacrimal involvement by Kimura disease is rare. We report two cases of Kimura's disease involving the orbit and eyelid , which has not been reported in korea. METHODS: A 16-year-old male patient presented with the chief complaint of upper eyelid swelling and ptosis that was first noticed 15 years ago. Another 16-year-old male patient visited our clinic with multiple nodules involving the head, neck, left upper arm, and the both upper eyelids . Ocular examination of case.1 revealed upper eyelid swelling and redness, painless nodule, and ptosis. In case 1. patient, Orbital MRI scan showed thickening of the superior, inferior, medial rectus muscle, levator palpebrae muscle, and a well-demarcated homogenous mass in the superonasal portion of the left orbit. RESULTS: Histopathologically, the lesions were characterized by lymphoid follicles, infiltration of many eosinophils, lymphocytes, abnormal capillary proliferation and fibrosis. Laboratory findings definitely revealed peripheral blood eosinophilia in both patients. CONCLUSIONS: Kimura's disease should be suspected and considered in the differential diagnosis for the patients with the eyelid swelling and mass.
