How to correct think about NSAIDs
- Author:
Huyen Tich Hoang
- Publication Type:Journal Article
- Keywords:
NSAID
- MeSH:
Anti-Inflammatory Agents, Non-Steroidal;
Pharmaceutical Preparations
- From:Journal of Vietnamese Medicine
1998;231(12):53-54
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Studies during 1970-1980 reported that 40% patients used the NAIDs suffered the gastrointestinal complication, commonly upper abdominal pain, dyspepsia; heart-burn and sour at least one time in the first week of drug administration occurred in 29% patients. About a haft million patients suffered the severe complications, even death due to the gastrointestinal toxicity of the drug. The discovering 2 subclasses of the cyclooxygenase enzyme COX and COX1 and new NSAIDs that have selective activity on the COX2 helped reducing significantly side effects of these valuable drugs. However any drug is always considered double way knife.
