Necrobiosis Lipoidica Over Surgical Scar in a Patient without Diabetes Mellitus.
- Author:
Min Won LEE
1
;
Young Gyun KIM
;
Jun Oh PAEK
;
Joung Soo KIM
;
Hee Joon YU
Author Information
1. Department of Dermatology, Hanyang University College of Medicine, Seoul, Korea. yuhjoon@hanyang.ac.kr
- Publication Type:Case Report
- Keywords:
Diabetes mellitus;
Necrobiosis lipoidica;
Scar
- MeSH:
Biopsy;
Cicatrix;
Collagen;
Dermis;
Diabetes Mellitus;
Giant Cells;
Granuloma;
Humans;
Lacerations;
Lower Extremity;
Lymphocytes;
Necrobiosis Lipoidica;
Necrobiotic Disorders;
Plasma Cells;
Skin Diseases;
Sutures;
Thigh
- From:Korean Journal of Dermatology
2013;51(8):639-642
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Necrobiosis lipoidica (NL) is a chronic granulomatous skin disease typified by indurated plaques on the shin. Although this condition is strongly associated with diabetes mellitus, its etiology and pathogenesis remains unknown. Localization of NL to the lower extremities suggests that local injury may be a contributing factor to the disease. A healthy 38-year-old man presented with localized erythematous to yellowish plaques on his right thigh that developed over several years. The lesion developed in the scar where suture had been done for laceration repair 25 years ago. A biopsy specimen showed degenerated collagen with surrounding palisading granulomas. Numerous lymphocytes and multinucleated giant cells were infiltrated throughout the reticular dermis. Plasma cells aggregation was found at the dermal subcutaneous junction.
