Primary Cutaneous Epithelioid Hemangioendothelioma That Mimicked Tufted Angioma Histopathologically.
- Author:
Su Young JEON
1
;
Ki Hoon SONG
Author Information
1. Department of Dermatology, Skin Cancer Center, College of Medicine, Dong-A University, Busan, Korea. khsong@dau.ac.kr
- Publication Type:Case Report
- Keywords:
Primary cutaneous epithelioid hemangioendothelioma;
Tufted angioma
- MeSH:
Biopsy;
Bone and Bones;
Capillaries;
Dermis;
Hemangioendothelioma, Epithelioid;
Hemangioma;
Humans;
Hyalin;
Liver;
Lung;
Male;
Skin Neoplasms;
Vacuoles;
von Willebrand Factor
- From:Korean Journal of Dermatology
2013;51(8):646-650
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Epithelioid hemangioendothelioma is a rare vascular tumor of endothelial origin that commonly occurs in the deep soft tissue, bone, lung, and liver, although cutaneous forms have rarely been reported. Tufted angioma (TA) is a rare slowly progressive vascular lesion characterized by multiple capillary tufts with the characteristic "canon-ball" appearance scattered throughout the dermis. A 35-year-old male presented a single, 2.5x1.5 cm sized, purpuric mass on the back. A biopsy specimen showed multiple lobules composed of epithelioid endotheial cells with intracytoplasmic vacuoles in a hyalinized and myxoid stroma, and large dilated vessels. The tumor cells were positive for CD31, CD34, and factor VIII-related Antigen, and the crescent shaped dilated vessels were negative for D2-40. We could not find any metastatic lesions on radiologic examinations. The patient was diagnosed with primary cutaneous epithelioid hemangioendothelioma. Herein, we present a rare and interesting case of primary cutaneous epithelioid hemangioendothelioma resembling TA histopathologically.
