A Case of Teratoma with Seminoma which Has Elevated Serum Alpha-FP and Beta-HCG.
- Author:
Dong Sun KIM
1
;
Jae Pil CHO
;
Gil Ho LEE
;
Duck Ki YOON
;
Sung Kun KOH
Author Information
1. Department of Urology, College of Medicine, Korea University, College of medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
seminoma;
alpha-fetoprotein
- MeSH:
alpha-Fetoproteins;
Carcinoma, Embryonal;
Carrier Proteins;
Choriocarcinoma;
Endodermal Sinus Tumor;
Female;
Gastrointestinal Tract;
Liver;
Neoplasms, Germ Cell and Embryonal;
Placenta;
Pregnancy;
Seminoma*;
Teratocarcinoma;
Teratoma*;
Trophoblasts;
Yolk Sac
- From:Korean Journal of Urology
1986;27(5):773-777
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Alpha-FP is a major serum binding protein produced by the fetal yolk sac, liver, and gastrointestinal tract. It may be produced by pure embryonal carcinoma, teratocarcinoma, yolk sac tumor, or combined tumors but not by pure choriocarcinoma or pure seminoma. HCG is secreted by the placenta but in germ cell tumors, syncytiotrophoblastic cells have been found responsible for the production of HCG. Recently, we experienced a case of mixed germ cell tumor composed of mainly teratoma and seminoma which is producing alpha-FP and beta-HCG.
