Multimodal Treatment of Pleuropulmonary Blastoma: Two case report.
- Author:
Joonseok PARK
1
;
Joungho HAN
;
Honghoe KOO
;
Jhingook KIM
Author Information
1. Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Korea. jkim@smc.samsung.co.kr
- Publication Type:Case Report
- Keywords:
Blastoma;
Pleural neoplasms
- MeSH:
Brain;
Chest Pain;
Child;
Combined Modality Therapy*;
Cough;
Drug Therapy;
Dyspnea;
Fever;
Humans;
Neoplasm Metastasis;
Pleural Neoplasms;
Respiratory Tract Infections;
Thorax
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
2003;36(8):614-618
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pleuropulmonary blastoma (PPB) is a rare intrathoracic neoplasm, found solely in childhood. The usual symptoms are dyspnea, chest discomfort, recurrent respiratory infections, fever, dry cough, and chest pain. The progress of PPB is usually aggressive and its progress is generally poor. Lymphatic spread to the hilar and mediastinal nodes can occur. Distant metastasis is found in brain, bones, and intra-abdominal organs. Surgical resection is the treatment of choice. When the disease is too extensive for surgical resection, neoadjuvant chemotherapy can be used. We report 2 cases of pleuropulmonary blastoma in children successfully treated with multimodal therapy.
