Evaluation of the Articular Involvement of Behcet's Disease Via Bone Scintigraphy.
- Author:
Eun Chun HAN
1
;
Sang Ho OH
;
Dongsik BANG
Author Information
1. Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea. dbang@yuhs.ac
- Publication Type:Original Article
- Keywords:
Articular involvement;
Behcet's disease;
Bone scintigraphy
- MeSH:
Animals;
Ankle;
Elbow;
Female;
Foot;
Hand;
Hip;
Humans;
Joints;
Knee;
Male;
Medical Records;
Sacroiliac Joint;
Shoulder;
Spine;
Wrist
- From:Korean Journal of Dermatology
2009;47(1):30-35
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Behcet's disease (BD) is a chronic relapsing inflammatory disease that involves various organ systems. Articular involvement was reported to be present in approximately 50% of Korean BD patients. The joint symptoms of BD patients have usually been described as intermittent, self-limiting and non-erosive, and they are mostly monoarticular and oligoarticular arthritis. OBJECTIVE: The purpose of our investigations was to evaluate the usefulness of bone scintigraphy for detecting the articular involvement of BD. METHODS: We reviewed the medical records, laboratory findings and bone scintigraphy findings of 89 patients who were diagnosed with BD from January 2005 to June 2007. RESULTS: Of the 89 BD patients, 14 patients were male and 75 patients were female with a mean age of 43.92+/-8.49 yr. The most frequently involved site on bone scintigraphy was the wrist (44.9%) with the decreasing order of frequency as follows: the feet (39.3%), the hands (25.8%), the knee (24.7%), the sacroiliac joint (22.4%), the shoulder (18%), the ankle (16.9%), the hip (12.6%), the spine (10%) and the elbow (3%). The pattern of involvement, which was defined as the number of joints showing hot uptake on the bone scintigraphy at one episode of arthropathy, was monoarticular in 5.6%, oligoarticular in 44.9%, polyarticular in 38.2% and there was no uptake in 11.2%. Among 130 joints, 63.1% of the joints showed close correlation between the clinical symptoms and the bone scintigraphy uptake. CONCLUSION: We suggest that bone scintigraphy can be a useful tool to determine the presence and site of articular involvement. However, more studies are needed to exclude non-specific bone scintigraphy uptake and to determine the correlation between clinical symptoms and the bone scintigraphy findings.
