Correlation of the Lewis Blood Group and the CEA Serum Level in Stomach Cancer Patients.
- Author:
Dong Won RYU
1
;
Sang Ho LEE
Author Information
1. Department of Surgery, Kosin University Colleage of Medicine, Busan, Korea. gslsh@ns.kosionmed.or.kr
- Publication Type:Original Article
- Keywords:
Lewis blood group;
Gastric cancer;
CEA
- MeSH:
Antibodies;
Blood Group Antigens;
Gastrectomy;
Humans;
Retrospective Studies;
Stomach Neoplasms*;
Stomach*
- From:Journal of the Korean Surgical Society
2007;73(1):27-30
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The purpose of our study was to compare the serum levels of CEA, CA19-9 and H.pylori antibody in patients with the Lewis (a+) blood group with that of the patients with the Lewis (a-) blood group. We also compared the outcome of the stomach cancer patients with the Lewis (b+) blood group with that of the stomach cancer patients with the Lewis (b-) blood group. METHODS: All of the 94 patients who underwent gastrectomy for stomach cancer at our hospital were retrospectively reviewed. The outcomes of the CEA, CA19-9 and H.pylori. antibody serum levels, the TNM stage, the ABO blood group and the Rh blood group were compared between the patients with the Lewis blood groups (a+) and (a-) and the patients with the Lewis blood groups (b+) and (b-), respectively. RESULTS: The mean serum level of CEA between the patients with the Lewis blood group (a+) and (a-) showed a statistical correlation (mean value: 5.51 ng/ml vs 3.25 ng/ml, respectively, P=0.016). But the mean serum level of CA19-9 and H.pylori. antibodies between the patients with the Lewis blood group (a+) and (a-) did not show a significant difference. The mean serum levels of CEA, CA19-9 and H.pylori antibodies between the patients with the Lewis blood group (b+) and (b-) did not show a significant difference. CONCLUSION: It was revealed that an elevated CEA level was related with the Lewis blood group (a), but this was not related with the Lewis blood group (b) in stomach cancer patients.
