Improvement of Eosinophilic Otitis Media by Optimized Asthma Treatment.
10.4168/aair.2013.5.3.175
- Author:
Yukako TANAKA
1
;
Manabu NONAKA
;
Yukie YAMAMURA
;
Etsuko TAGAYA
;
Ruby PAWANKAR
;
Toshio YOSHIHARA
Author Information
1. Department of Otolaryngology, Tokyo Women's Medical University School of Medicine, Tokyo, Japan. nonaka-m@oto.twmu.ac.jp
- Publication Type:Case Report
- Keywords:
Eosinophilic otitis media;
asthma;
inhalation therapy
- MeSH:
Adrenal Cortex Hormones;
Androstadienes;
Asthma;
Diethylpropion;
Ear, Middle;
Eosinophilia;
Eosinophils;
Eustachian Tube;
Nasal Mucosa;
Nasopharynx;
Otitis;
Otitis Media;
Respiratory System;
Respiratory Therapy;
Rhinitis;
Rhinitis, Allergic, Perennial;
Seasons;
Fluticasone
- From:Allergy, Asthma & Immunology Research
2013;5(3):175-178
- CountryRepublic of Korea
- Language:English
-
Abstract:
Eosinophilic otitis media (EOM) shows a very high rate of association with asthma, and intractable otitis media involves marked eosinophil infiltration into the middle ear. The middle ear space is connected to the nasopharynx by the Eustachian tube, and it is considered a part of the upper respiratory tract. Allergic rhinitis and asthma often coexist as chronic inflammatory diseases of the upper and lower airways, respectively, and have an impact on each other. In fact, inhaled corticosteroids reduce seasonal eosinophilia systemically in the circulation and locally in the nasal mucosa, as well as attenuate seasonal nasal symptoms. We report a case of EOM associated with adult-onset asthma that improved following optimal asthma therapy after changing the treatment from inhaled fluticasone propionate (FP) (200 microg b.i.d.) to a combination of FP/salmeterol (250/50 microg b.i.d.). This result supports the hypothesis that EOM and asthma are closely linked, presenting as different manifestations of a similar disease syndrome.
