H+ -ATPase Pump Defects of Distal Renal Tubular Acidosis as Initial Manifestation of Systemic Lupus Erythematosus.
- Author:
Young Jun SONG
1
;
Jung Eun KIM
;
Jong Woo LEE
;
Dong Hun LEE
;
Hyeon Kyeong CHO
;
Gyu Tae SHIN
;
Heungsoo KIM
;
Hyunee YIM
;
Jin KIM
;
Sun Woo IM
;
Wan Young KIM
Author Information
1. Department of Internal Medicine, School of Medicine, Ajou University, Suwon, Korea. nephrohs@ajou.ac.kr
- Publication Type:Case Report
- Keywords:
Distal renal tubular acidosis;
Initial manifestation of systemic lupus erythematosus;
H+-ATPase pump defects
- MeSH:
Acidosis, Renal Tubular*;
Arthritis;
Diagnosis;
Emergency Service, Hospital;
Female;
Fever;
Humans;
Lupus Erythematosus, Systemic*;
Muscle Weakness;
Young Adult
- From:Korean Journal of Nephrology
2003;22(1):148-155
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Systemic lupus erythematosus (SLE) is a multisystem disease with marked variability in its manifestation. Tubulointerstitial involvement is well recognized in SLE. But usually the tubular dysfunction is latent and usually presents after diagnosis of SLE. We report a 20 years old female whose initial symptom of SLE was distal renal tubular acidosis (RTA). She presented with severe muscle weakness at emergency room with laboratory fingding consistent with distal RTA. After several months she developed fever, arthritis, serologic fingding which was compatible to diagnose SLE. We report a case whose initial symptom of SLE had been distal RTA.
