A Comparison of Clinical Outcomes for Breast-conserving Treatment and Mastectomy for Early Breast Cancer.
10.3857/jkstro.2008.26.1.10
- Author:
Jae Myoung NOH
1
;
Won PARK
;
Seung Jae HUH
;
Doo Ho CHOI
;
Jung Hyun YANG
;
Seok Jin NAM
;
Jeong Han KIM
;
Young Hyuck IM
;
Jin Seok AHN
Author Information
1. Department of Radiation Oncology, Sungkyunkwan University School of Medicine, Seoul, Korea. wonro.park@samsung.com
- Publication Type:Original Article
- Keywords:
Breast cancer;
Breast-conserving surgery;
Mastectomy
- MeSH:
Breast Neoplasms
- From:The Journal of the Korean Society for Therapeutic Radiology and Oncology
2008;26(1):10-16
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To compare the treatment outcomes and to analyze prognostic factors between the use of a breast-conserving treatment (BCT) and a mastectomy for early stage breast cancer. MATERIALS AND METHODS: We retrospectively reviewed 1,200 patients with pathological stage T1-2N0 breast cancer who received surgery between September 1994 and December 2002 at Samsung Medical Center. We compared the patient characteristics and treatment outcomes between the two treatment groups. RESULTS: Among the 1,174 eligible patients, 601 (51.2%) patients received a BCT and the remaining 573 (48.8%) patients received a mastectomy. The mastectomy group of patients had significantly more cases with a larger tumor size, multicentricity, extensive intraductal component, and estrogen- and progesterone-receptor negativity. The ten-year overall survival rates (OS) of the BCT and mastectomy groups were 91.96% and 91.01%, respectively (p=0.1274). The ten-year disease-free survival rates (DFS) were 80.48% for the BCT group of patients and 84.95% for the mastectomy group of patients, respectively (p=0.8795). CONCLUSION: Our study shows some differences in patient characteristics between the two treatment groups. However, these differences did not result in significant survival differences.
