Acute Renal Failure in Children: Underlying Disease and Management according to Age.
- Author:
Eun Joung PARK
1
;
Joung Sim KIM
;
Jai Bok YOO
;
Joung Sook SUL
;
Si Whan KOH
;
Phil Soo OH
;
I Suk KANG
;
Moon Soo PARK
;
Heung Jae LEE
;
Dong Kyoo JIN
Author Information
1. Department of Pediatrics, Sung Kyun Kwan University, College of Medicine.
- Publication Type:Original Article
- Keywords:
Acute renal failure children;
Age;
Underlying disease;
Management
- MeSH:
Acute Kidney Injury*;
Age Factors;
Child*;
Gastrointestinal Diseases;
Heart;
Hemolytic-Uremic Syndrome;
Humans;
Critical Care;
Intensive Care Units;
Lupus Erythematosus, Systemic;
Mortality;
Multiple Organ Failure;
Retrospective Studies;
Seoul
- From:Journal of the Korean Pediatric Society
1998;41(5):654-662
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: It has been stressed that age itself as well as multiple organ failure are important prognostic factors in acute renal failure (ARF) in children. This study was performed to find out the significance of age factor and underlying disease of ARF in children. METHODS: We tried to review 58 pediatric ARF cases, retrospectively, in the pediatric intensive care unit (excluding the neonatal and surgical intensive care unit cases) of the Samsung Seoul Hospital of Sung Kyun Kwan University from Sept., 1994. to Dec., 1996. RESULTS: We classified the enrolled 58 cases into 5 age groups and more than half were younger than 1 year old. As underlying causes, heart and gastrointestinal disease were predominant in less than 1 month of age group. After 1 year of age, intrinsic renal disease was the most common cause (43-50%). Among the renal disease, systemic lupus erythematosus (10-15 year group), hemolytic uremic syndrome (1-10 year group), and obstructive uropathy (less than 1 year age group) were common etiologies. The mortality was the highest (46.7%) in less than 1 year group and lowest (21.4%) in 10-15 year age group. CONCLUSION: The underlying disorders of ARF in children were different among the age group. Among intrinsic renal diseases, hemolytic uremic syndrome was the most common cause. The difference in the mortality was dependent on age and underlying disease.
