Prevalence and Risk Factors of Early-Stage Age-Related Macular Degeneration in Patients Examined at a Health Promotion Center in Korea.
10.3346/jkms.2012.27.5.537
- Author:
Byung Gil MOON
1
;
Soo Geun JOE
;
Jong uk HWANG
;
Hong Kyu KIM
;
Jaewon CHOE
;
Young Hee YOON
Author Information
1. Department of Ophthalmology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. yhyoon@amc.seoul.kr
- Publication Type:Original Article
- Keywords:
Age-Related Macular Degeneration;
Gealth Screening Examination;
Risk Factors
- MeSH:
Age Factors;
Cohort Studies;
Community Health Centers;
Female;
Humans;
Hyperlipidemias/complications;
Macular Degeneration/complications/diagnosis/*epidemiology;
Male;
Middle Aged;
Odds Ratio;
Prevalence;
Questionnaires;
Republic of Korea/epidemiology;
Retrospective Studies;
Risk Factors;
Sex Factors;
Smoking
- From:Journal of Korean Medical Science
2012;27(5):537-541
- CountryRepublic of Korea
- Language:English
-
Abstract:
We evaluated the prevalence and risk factors for early age-related macular degeneration (AMD) in Koreans 50 yr of age or older who were examined at a single health promotion center. We retrospectively reviewed the records of 10,449 subjects who visited the center over a 6-month period. Fundus photography was performed on all subjects, and systematic risk factor analysis was conducted using a structured questionnaire. All patients (n = 322) were initially diagnosed with drusen or early AMD using fundoscopy; the control group (n = 10,127) were those yielding normal fundoscopy findings. The age- and gender-adjusted prevalence of early AMD was 3.08%. Advanced age, male gender, smoking status, hyperlipidemia, working outdoors, and residence in rural areas were all significantly associated with an increased risk for development of early AMD. Higher-level ingestion of fruit or herbal medication and an increased amount of exercise were associated with a lower risk of early AMD development. In our Korean cohort, consisting principally of relatively healthy, middle-class urban adults, the prevalence of early AMD was 3.08% that is similar to that reported in earlier epidemiological studies. Several modifiable risk factors such as smoking and hyperlipidemia are associated with the prevalence of early AMD in our cohort.
