Unolateral Aldosterone-producing Adenoma with a Contralateral Black Adenoma.
- Author:
Eun Young OH
1
;
Myung Shik LEE
;
Young Hee LIM
;
Soo Jung KANG
;
Jung Hak CHUN
;
Byoung Joon KIM
;
Jae Hoon CHUNG
;
Yong Ki MIN
;
Moon Kyu LEE
;
Kwang Won KIM
;
Jung Hyun YANG
Author Information
1. Department of Medicine, Sungkyunkwan University College of Medicine, Samsung Medical Center, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Aldosteronism;
Bilateral adrenal adenoma;
Black adenoma
- MeSH:
Adenoma*;
Adult;
Aldosterone;
Autopsy;
Discrimination (Psychology);
Female;
Humans;
Hyperaldosteronism;
Hyperplasia;
Hypertension;
Renin;
Tomography, X-Ray Computed
- From:Journal of Korean Society of Endocrinology
1999;14(1):177-182
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary aldosteronism due to unilateral adenoma is a rare cause of surgically curable hypertension. Bilateral adrenal mass has occasionally been reported in this syndrome, and bilateral aldosterone-producing adenoma (APA), or bilateral adrenal nodular hyperplasia have been demonstrated in some cases. However, another possibility is the coexistence of a unilateral APA with a contralateral benign or metastatic nonfunctioning mass, because adrenal tumors are frequently found at autopsy or incidentally detected during abdominal morphological evaluation in patients without adrenal dysfunction. A 39 year-old woman presented with hyperaldosteronism, suppressed renin levels, and bilateral adrenal mass on adrenal CT scanning. Selective adrenal venous sampling was unsuccessful in demonstrating concentration gradient of aldosterone. Postoperative measurement of hormone content in the tumor extract revealed unilateral aldosteron-producing adenoma with contralateral nonfunctioning black adenoma, Determination of hormone content in the tumor extract could be useful for the discrimination of functioning and nonfunctioning endocrine tumors, particularly in case of multiple tumors.
