Prognostic factors of breast cancer in Koreans.
- Author:
Hark Kyun KIM
1
;
Soo Mi BANG
;
Jae Ho BYUN
;
Min Hee RYU
;
Won Sup LEE
;
Keun Seok LEE
;
Joo Young JEONG
;
Jee Hyun KIM
;
Se Hoon LEE
;
Im Il NA
;
Dae Seog HEO
;
Young Jue BANG
;
Noe Kyeong KIM
Author Information
1. Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Prognostic factor;
Breast cancer
- MeSH:
Breast Neoplasms*;
Breast*;
Estrogens;
Humans;
Lymph Nodes;
Mastectomy;
Medical Records;
Multivariate Analysis;
Proportional Hazards Models;
Survival Rate
- From:Korean Journal of Medicine
2000;58(4):446-452
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The aim of this study is to determine prognostic factors of breast cancer in Korean patients who underwent curative mastectomy. METHODS: Medical records of 181 patients who underwent curative mastectomy were reviewed. Relapse-free survival and overall survival were documented for each patient. Factors influencing survival were analyzed using Cox proportional hazard model. RESULTS: Overall 5-year survival rate was 82.0%, and 8-year survival rate was 74.7%. Multivariate analysis indicated that multiple axillary lymph node involvement (> or =4), postmenopausal status, and negative estrogen receptor were independent adverse prognostic factors. The adjusted relative risks of multiple axillary lymph node involvement (> or =4), postmenopausal status, and negative estrogen receptor were estimated 2.60 (95% Confidence Interval (CI): 1.28-5.30), 2.64 (95% CI: 1.46-4.79), and 2.27 (95% CI: 1.19-4.35), respectively. CONCLUSION: Multiple axillary lymph node involvement (> or =4), postmenopausal status, and negative estrogen receptor were independent adverse prognostic factors in Korean breast cancer patients after curative mastectomy.
