Body composition: A predictive factor of cycle fecundity.
10.5653/cerm.2014.41.2.75
- Author:
Semra KAYATAS
1
;
Aysen BOZA
;
Murat API
;
Didar KURT
;
Mustafa EROGLU
;
Sevcan Arzu ARINKAN
Author Information
1. Department of Obstetrics and Gynecology, Zeynep Kamil Women and Children Diseases Training and Research Hospital, Istanbul, Turkey. arcke83@gmail.com
- Publication Type:Original Article
- Keywords:
Bioelectrical impedance;
Fat mass;
Fecundity;
Infertility;
Unexplained
- MeSH:
Adipose Tissue;
Body Composition*;
Body Mass Index;
Electric Impedance;
Female;
Fertility*;
Humans;
Infertility;
Insemination;
Observational Study;
Pregnancy;
Pregnant Women;
Prospective Studies;
Reproduction;
ROC Curve;
Sensitivity and Specificity
- From:Clinical and Experimental Reproductive Medicine
2014;41(2):75-79
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: To study the effect of body composition on reproduction in women with unexplained infertility treated with a controlled ovarian hyperstimulation and intrauterine insemination programme. METHODS: This prospective observational study was conducted on 308 unexplained infertile women who were scheduled for a controlled ovarian hyperstimulation and intrauterine insemination programme and were grouped as pregnant and non-pregnant. Anthropometric measurements were performed using TANITA-420MA before the treatment cycle. Body composition was determined using a bioelectrical impedance analysis system. RESULTS: Body fat mass was significantly lower in pregnant women than in non-pregnant women (15.61+/-3.65 vs.18.78+/-5.97, respectively) (p=0.01). In a multiple regression analysis, body fat mass proved to have a stronger association with fecundity than the percentage of body fat, body mass index, or the waist/hip ratio (standardized regression coefficient> or =0.277, t-value> or =2.537; p<0.05). The cut-off value of fat mass, which was evaluated using the receiver operating characteristics curve, was 16.65 with a sensitivity of 61.8% and a specificity of 70.2%. Below this cut-off value, the odds of the pregnancy occurrence was found to be 2.5 times more likely. CONCLUSION: Body fat mass can be predictive for pregnancy in patients with unexplained infertility scheduled for a controlled ovarian hyperstimulation and intrauterine insemination programme.
