Subcorneal pustular dermatosis in a dog.
- Author:
Seong Jun PARK
1
Author Information
1. College of Veterinary Medicine, Research Institute of Veterinary Medicine, Chungnam National University, Daejeon 305-764, Korea. parksj@cnu.ac.kr
- Publication Type:Case Report
- Keywords:
dapsone;
dog;
subcorneal pustular dermatosis
- MeSH:
Administration, Oral;
Animals;
Dapsone;
Dogs;
Female;
Fluorescent Antibody Technique, Direct;
Humans;
Immunoglobulin A;
Immunoglobulin G;
Immunoglobulin M;
Neutrophils;
Pemphigus;
Skin;
Skin Diseases;
Skin Diseases, Vesiculobullous
- From:Korean Journal of Veterinary Research
2013;53(2):125-127
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Canine Subcorneal pustular dermatosis (CSPD) represents a sterile, superficial, pustular skin disease of unknown cause but may be a variant of pemphigus foliaceus. A 7-year-old, intact female, mixed dog presented with 3-month history of pruritic multiple pustules and crusts. Direct smears from intact pustules revealed numerous nondegenerate neutrophils, some acantholytic cells, and bacterial culture was negative. Histologic examination of lesional skin showed subcorneal pustules filled with neutrophils and acantholytic cells. The direct immunofluorescence tests stained with IgG, IgA, IgM, C3 were negative. Oral administration of dapsone (1 mg/kg/q8h) was initiated and it was reduced to 1 mg/kg/q12h with good control of the lesions.
