Personalized treatment of hepatitis B.

Author: Anna S LOK ¹
Author Information

1. Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, MI, USA. aslok@umich.edu
Publication Type:Review
Keywords: Hepatitis B virus; Chronic hepatitis B; Management; Personalized medicine
MeSH: Antiviral Agents/*therapeutic use; Genotype; Hepatitis B/complications/*drug therapy; Hepatitis B virus/genetics; Humans; Liver Diseases/etiology; *Precision Medicine; Risk Factors
From:Clinical and Molecular Hepatology 2015;21(1):1-6
CountryRepublic of Korea
Language:English
Abstract: There are seven approved drugs for treatment of hepatitis B. Professional guidelines provide a framework for managing patients but these guidelines should be interpreted in the context of the individual patient's clinical and social circumstances. Personalized management of hepatitis B can be applied based on prediction of the individual patient's risk of cirrhosis and hepatocellular carcinoma to guide the frequency and intensity of monitoring and urgency of treatment. It can also be applied to decisions regarding when to start treatment, which drug to use, and when to stop based on the individual patient's disease characteristics, preference, comorbidities and other mitigating circumstances.