Aortic Aneurysm Screening in a High-Risk Population: A Non-Contrast Computed Tomography Study in Korean Males with Hypertension.
10.4070/kcj.2014.44.3.162
- Author:
In Jeong CHO
1
;
Sung Yeol JANG
;
Hyuk Jae CHANG
;
Sanghoon SHIN
;
Chi Young SHIM
;
Geu Ru HONG
;
Namsik CHUNG
Author Information
1. Division of Cardiology, Severance Cardiovascular Hospital, Seoul, Korea. hjchang@yuhs.ac
- Publication Type:Original Article
- Keywords:
Aorta;
Aneurysm;
Prevalence;
Computed tomography
- MeSH:
Aged;
Aneurysm;
Aorta;
Aorta, Abdominal;
Aortic Aneurysm*;
Aortic Valve;
Blood Pressure;
Body Surface Area;
Dyslipidemias;
Humans;
Hypertension*;
Logistic Models;
Male;
Mass Screening*;
Prevalence;
Prospective Studies;
Risk Factors
- From:Korean Circulation Journal
2014;44(3):162-169
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND AND OBJECTIVES: Screening strategies for aortic aneurysm (AA) according to risk factors and ethnicity are controversial. This study explored the prevalence of AA and determined whether screening is necessary in a population of multiple risk factors. SUBJECTS AND METHODS: From June, 2012 to April, 2013, 542 consecutive elderly (> or =65 years) male hypertensive patients without a history of AA were prospectively enrolled. After excluding 15 patients (2.8%) with aortic valve surgery, 30 patients (5.5%) with suboptimal computed tomography (CT) images, the remaining 496 patients (age 73+/-5 years) comprised the study population. Maximal diameters of the thoracic and abdominal aorta were measured using non-contrast CT. RESULTS: The prevalence of thoracic AA (TAA, diameter > or =40 mm) and abdominal AA (AAA, diameter > or =30 mm) was 36.5% (181/496) and 6.0% (30/496), respectively. In the multivariate logistic regression analysis, determinants for TAA were age {odds ratio (OR) 1.059, 95% confidence interval (CI) 1.018-1.101, p=0.005}, dyslipidemia (OR 0.621, 95% CI 0.418-0.923, p=0.018), body surface area (OR 11.92, 95% CI 2.787-50.97, p=0.001), diastolic blood pressure (OR 1.029, 95% CI 1.009-1.049, p=0.004) and AAA (OR 3.070, 95% CI 1.398-6.754, p=0.005). In contrast, AAA was independently associated with dysplipidemia (OR 2.792, 95% CI 1.091-7.143, p=0.032), current/past smokerfs (OR 4.074, 95% CI 1.160-14.31, p=0.028), and TAA (OR 3.367, 95% CI 1.550-7.313, p=0.002). CONCLUSION: The prevalence of AA was significant and TAA was more prevalent than AAA in elderly Korean males with hypertension. Future research should establish distinct screening strategies for TAA and AAA according to risk factors and ethnicity.
