Cytomorphological Findings and Histological Correlation of Low-Grade Cribriform Cystadenocarcinoma of Salivary Gland in Fine-Needle Aspiration: A Case Study.
- Author:
Young Sin KO
1
;
Ja Seung KOO
Author Information
1. Department of Pathology, Yonsei University College of Medicine, Seoul, Korea. kjs1976@yuhs.ac
- Publication Type:Case Report
- Keywords:
Biopsy, fine-needle;
Low-grade cribriform cystadenocarcinoma;
Salivary glands
- MeSH:
Biopsy, Fine-Needle*;
Cheek;
Cystadenocarcinoma*;
Diagnosis;
Epithelial Cells;
Humans;
Korea;
Middle Aged;
Parotid Gland;
Salivary Glands*
- From:Korean Journal of Pathology
2013;47(6):592-595
- CountryRepublic of Korea
- Language:English
-
Abstract:
Low-grade cribriform cystadenocarcinoma (LGCCC) of the salivary gland is a rare tumor. We report the cytologic features and histologic correlation of a patient with LGCCC. A 57-year-old man had a hardly palpable, nontender mass in the right cheek area followed over nine months. Radiologic analysis revealed a 1.2 cm multiseptated, cystic, solid nodule in an anterior superficial lobe of the right parotid gland. Fine-needle aspiration cytology revealed many irregular overlapping sheets or clusters of ductal epithelial cells forming solid, pseudopapillary, and cribriform architectures. Nuclei of the tumor cells revealed inconspicuous atypia with minimal size variation. On the basis of these findings, we confirmed a diagnosis of ductal epithelial proliferative lesion, favoring neoplasm, with uncertain malignant potential. Tumor excision was performed, revealing a tiny multicystic nodule (0.7 cm). Histopathologically, this tumor showed the characteristic morphology of LGCCC. This is the first report of cytomorphological findings of LGCCC in Korea.
