The Survey of Prevalence of Osteoporosis in Alzheimer's Disease Patients.
- Author:
Yeob KIM
1
;
Ki Yong AHN
;
Tae Hyun YOON
;
Che Jun LIM
;
Woo Jin SHIN
Author Information
1. Department of Orthopaedics, Seonam University Nam-Kwang Hospital, Kwangju, Korea. mdaky@hanmail.net
- Publication Type:Original Article
- Keywords:
Alzheimer disease;
Osteoporosis;
Prevalence
- MeSH:
Alzheimer Disease;
Bone Density;
Bone Diseases, Metabolic;
Humans;
Osteoporosis;
Prevalence;
Spine
- From:Korean Journal of Bone Metabolism
2011;18(2):125-130
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: To evaluate the prevalence of osteoporosis in the Alzheimer's disease patients. METHODS: One hundred and twenty eight patients with Alzheimer's disease were included in this study. The patients are diagnosed with Alzheimer's disease using Korean-Mini Mental Status Examination (K-MMSE) and checked bone mineral density using single-energy (SE) quantitative computed tomography (QCT) in 2010. To define abnormality in terms of QCT of the spine, a bone mineral density (BMD) spine below 80 mg/cm3 is indicative of osteoporosis and BMD between 80 and 120 mg/cm3 is indicative osteopenia. RESULTS: The prevalence of osteoporosis in the control group is 29.73%. The prevalence of osteoporosis in the Alzheimer's disease patients is 96.87%. The prevalence of osteopenia in the Alzheimer's disease patients is 3.12%. The prevalence of severe osteoporosis fracture in the Alzheimer's disease patients is 32.03%. CONCLUSION: The prevalence of osteoporosis in Alzheimer's disease patients is higher than in the control group.