Serum CA 19-9 levels in patients with endometriosis.
- Author:
Young Min CHOI
1
;
Yoo Kyung SOHN
;
Tai Jun KIM
;
Seung Yup KU
;
Kwang Bum BAI
;
Chang Suk SUH
;
Seok Hyun KIM
;
Jung Gu KIM
;
Shin Yong MOON
;
Jin Yong LEE
Author Information
1. Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
endometriosis;
CA19-9;
CA125;
tumor marker
- MeSH:
Classification;
Endometriosis*;
Female;
Fertility;
Humans;
Retrospective Studies
- From:Korean Journal of Obstetrics and Gynecology
2002;45(12):2231-2235
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: To explore the efficacy of serum CA19-9 determination for the detection of endometriosis. DESIGNS: A retrospective analysis. MATERIALS AND METHODS: Preoperative serum CA19-9 and CA125 concentrations were measured in 53 patients with surgically and/or histologically diagnosed endometriosis. The extent of disease was staged according to the revised American Fertility Society (1985) classification system. RESULTS: Serum CA19-9 levels were elevated (>or=37 U/ml) in 13 (24.5%) out of 53 patients with endometriosis and serum CA125 levels were elevated (>or=35 U/ml) in 13 (24.5%). Either CA19-9 or CA125 levels in serum were elevated in 18 (34.0%) patients. In patients with stage III or IV endometriosis, elevated CA19-9 levels were noted in 11 (31.4%) of 35 patients, while CA125 in 12 (34.3%). Either CA19-9 or CA125 levels in serum were elevated in 15 (42.9%) of 35 patients with stage III or IV. CONCLUSION: These results suggest that serum CA19-9, in addition to CA125, measurement could help in identifying patients with moderate to severe endometriosis.
