Oculopharyngeal Palsy in Patients with Coexistence of Anti-GQ1b and GT1a Antibodies.
- Author:
Jae Yong SHIN
1
;
Young Eun PARK
;
Hye Kyoung SHIN
;
Kee Yong CHO
;
Jong Kuk KIM
;
Dae Seong KIM
Author Information
1. Department of Neurology, Pusan National University School of Medicine, Busan, Korea. yepark407@gmail.com
- Publication Type:Case Report
- Keywords:
Guillain-Barre syndrome;
Anti-GQ1b antibody;
Anti-GT1a antibody
- MeSH:
Antibodies*;
Ataxia;
Facial Paralysis;
Guillain-Barre Syndrome;
Humans;
Miller Fisher Syndrome;
Ophthalmoplegia;
Paralysis*
- From:Journal of the Korean Neurological Association
2014;32(4):275-278
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The presence of antiganglioside antibodies is closely associated with the clinical characteristics of Guillain-Barre syndrome (GBS), as evidenced by the presence of anti-GQ1b antibody in Miller-Fisher syndrome and anti-GT1a antibody in a pharyngeal-cervical-brachial variant of GBS. We report herein three patients harboring both anti-GT1a and anti-GQ1b antibodies who all exhibited oculopharyngeal palsy and additional features of ataxia, facial palsy, internal ophthalmoplegia, and visual disturbance. The findings of this study suggest that oculopharyngeal palsy is a common clinical manifestation determined by the coexistence of anti-GQ1b and GT1a antibodies.
