Two Cases of Wernicke's Encephalopathy in Young Age Patients Receiving Allogeneic Hematopoietic Stem Cell Transplantation.
10.3349/ymj.2012.53.5.1049
- Author:
Jung Woo HAN
1
;
Seungtaek LIM
;
Hye Sun SHIN
;
Hee Jin PARK
;
Won Jai JUNG
;
Seung Yeon KWON
;
Chuhl Joo LYU
Author Information
1. Division of Medical Oncology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Case Reports
- Keywords:
Wernicke encephalopathy;
thiamine;
hematopoietic stem cell transplantation
- MeSH:
Ataxia;
Early Diagnosis;
Hematopoietic Stem Cell Transplantation*;
Hematopoietic Stem Cells*;
Humans;
Parenteral Nutrition, Total;
Thiamine;
Thiamine Deficiency;
Wernicke Encephalopathy*
- From:Yonsei Medical Journal
2012;53(5):1049-1053
- CountryRepublic of Korea
- Language:English
-
Abstract:
Wernicke's encephalopathy is an acute neurolopsychiatric syndrome caused by thiamine deficiency, and classically presents with the triad of opthalmopathy, ataxia and altered mentality. Both prolonged total parenteral nutrition and reduced oral intake can induce Wernicke's encephalopathy during hematopoietic stem cell transplantation (HSCT). Although early treatment is important for recovery from Wernicke's encephalopathy, the vague symptoms and characteristics hinder early diagnosis. Furthermore, Wernicke's encephalopathy is not infrequent and can develop at any age during HSCT. Herein, we present two young patients developing Wernicke's encephalopathy during HSCT.
