Medulloblastoma:Outcome and Prognostic Factors.
- Author:
Soo Han YOON
1
;
Kyu Sung LEE
;
Yong Gou PARK
;
Joong Uhn CHOI
;
Sang Sup CHUNG
;
Kyu Chang LEE
Author Information
1. Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Brain tumor;
Medulloblastoma;
Radiation therapy;
Chemotherapy;
Prognosis
- MeSH:
Brain Neoplasms;
Disease-Free Survival;
Drug Therapy;
Follow-Up Studies;
Humans;
Medulloblastoma;
Neurosurgery;
Prognosis;
Recurrence
- From:Journal of Korean Neurosurgical Society
1993;22(2):188-198
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
43 patients with medulloblastoma of the posterior fossa were treated at the Department of Neurosurgery Yonsei University College of Medicine from 1981 to 1991. Major treatment were surgery, irradiation, chemotherapy or combination. Mean follow-up was 30 months(range, 1 to 120 months). Kaplan-Meier actuarial survival for all patients 59% at 3 years. Disease free survival was 53% at 3 years. Radiation and treatment period(before 1986 vs after 1986) affected outcome significantly. But other prognosic factors such as age, extent of surgical resection and chemotherapy did not affect outcome statistically. Follow-up more than 3 years showed very low recurrence rate.
