Clinical Analysis of Stereotactic Brachytherapy with High-Activity Iridium-192 Sources for Treatment of Malignant Astrocytomas.
- Author:
Sun Hee LEE
1
;
Eun Ik SON
;
Jang Chull LEE
;
Dong Won KIM
;
Man Bin YIM
;
In Hong KIM
;
Tae Jin CHOI
;
Ok Bae KIM
Author Information
1. Department of Neurosurgery, School of Medicine, Keimyung University, Taegu, Korea.
- Publication Type:Original Article
- Keywords:
Interstitial brachytheraphy;
High-activity iridium-192;
Malignant astrocytoma
- MeSH:
Astrocytoma*;
Brachytherapy*;
Follow-Up Studies;
Glioblastoma;
Humans;
Pathology;
Patient Selection;
Random Allocation
- From:Journal of Korean Neurosurgical Society
1993;22(2):252-260
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Interstitial irradiation using high-activity Iridium-192 sources was studied clinically to treat supratentorial malignant astrocytomas(including glioblastoma multifrome). As of 1988, in attempt to define the efficacy of this technique in patients with more extensive disease, we treated patients less rigid selection criteria. 15 eligible patients have been approached and ten have accepted randomization for follow-up study over two years. Pathology was anaplastic astrocytoma in 5 patients, glioblastoma multiforme in 5 patients. Mean survival of patients treated with this procedure was 18.4 months. Continued investigation will determine which patient may benefit from this techique.
