A Case of Non-occulsive Mesentery Ischemia with Pulmonary Embolism due to Protein C Deficiency.
10.4166/kjg.2010.55.3.194
- Author:
Tae Wan KIM
1
;
Sung Youn CHOI
;
Im Ju KANG
;
Yoon Jung KANG
;
Dong Hyuk SHIN
Author Information
1. Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
- Publication Type:Case Report ; English Abstract
- Keywords:
Protein C deficiency;
Ischemia, Mesentery;
Pulmonary embolism
- MeSH:
Colonoscopy;
Humans;
Ischemia/*diagnosis/etiology;
Magnetic Resonance Angiography;
Male;
Mesenteric Veins;
Middle Aged;
Protein C Deficiency/*complications/genetics;
Pulmonary Embolism/*diagnosis/etiology/radiography;
Tomography, X-Ray Computed
- From:The Korean Journal of Gastroenterology
2010;55(3):194-197
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Protein C is an important physiological anticoagulant factor. Protein C deficiency has been linked to venous thrombosis at unusual sites, including the cerebral and mesenteric veins. Hereditary protein C deficiency is inherited primarily as an autosomal dominant trait with incomplete penetrance. Protein C and S deficiencies are known to increase the risk of venous thrombosis and pulmonary thromboembolism. Testing for protein C levels and function is necessary for the detection of both type I and type II protein C deficiency. In this article, we report a case of pulmonary embolism and mesentery ischemia due to type 1 protein C deficiency.
