Development of juvenile rheumatoid arthritis in a patient with multiple sclerosis.
- Author:
Soo Young MOON
1
;
Yeon Ah LEE
;
Joonbeom SHIN
;
Sang Hoon LEE
;
Seung Jae HONG
;
Hyung In YANG
Author Information
1. Department of Internal Medicine, Kyunghee University School of Medicine, Seoul, Korea. aprildaum@hanmail.net
- Publication Type:Case Report
- Keywords:
Multiple sclerosis;
juvenile rheumatoid arthritis
- MeSH:
Arthritis, Juvenile Rheumatoid;
Arthritis, Rheumatoid;
Central Nervous System;
Demyelinating Diseases;
Humans;
Multiple Sclerosis;
Sclerosis;
T-Lymphocytes;
Tumor Necrosis Factor-alpha
- From:Korean Journal of Medicine
2008;74(1):106-109
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Multiple sclerosis (MS) is an immune-mediated, inflammatory demyelinating disease of the central nervous system. The coexistence of multiple sclerosis and rheumatoid arthritis is very rare. This rare association is interesting due to the overlapping pathophysiological similarities of T-cells and tumor necrosis factor-alpha (TNF-alpha) in both diseases. We report a case of a Korean 10 year old girl with multiple sclerosis, who after 3 years developed a clinical and serological manifestation of juvenile rheumatoid arthritis.