Long-Term Endothelial Cell Changes after Angle-Supported Anterior Chamber Lens Implantation in Phakic Eyes.
10.3341/jkos.2012.53.2.208
- Author:
Jenny YANG
1
;
Jin Ki LEE
Author Information
1. Department of Ophthalmology, Daegu Fatima Hospital, Daegu, Korea. cornea21@hanmail.net
- Publication Type:Original Article
- Keywords:
Angle-supported anterior chamber lens;
Endothelial cell loss
- MeSH:
Anterior Chamber;
Endothelial Cells;
Eye;
Follow-Up Studies;
Humans;
Microscopy;
Retrospective Studies
- From:Journal of the Korean Ophthalmological Society
2012;53(2):208-214
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate long-term endothelial cell changes in phakic eyes that underwent implantation of an angle-supported anterior chamber lens to correct myopia. METHODS: A retrospective analysis was performed in 110 eyes of 55 patients who underwent implantation of angle-supported anterior chamber lenses with a follow-up period longer than 5 years. Comparisons were made between preoperative and postoperative endothelial cell density, coefficient of variation, and percentage of hexagonal cells. RESULTS: Mean preoperative corneal endothelial cell density was 2951 +/- 336 cells/mm2 and the percentage of cell loss was 3.8% at year 1, 12.6% at year 3, 13.4% at year 5, 22.5% at year 7, and 22.2% at year 9. Explantation was required in 13 eyes (11.8%) due to the decrease of endothelial cell count to 936 +/- 458 cells/mm2 over 9 years of follow-up. CONCLUSIONS: Continuous endothelial cell loss was observed after implantation of angle-supported anterior chamber lens in the long-term follow-up. A constant decline in the endothelial cell density necessitates periodic ophthalmologic evaluation including specular microscopy.
