Paradoxical Deterioration of Intramedullary Spinal Tuberculomas during Antituberculous Therapy.
- Author:
Keum Jun JANG
1
;
Cheol Su JWA
;
Kang Hyun KIM
;
Jae Kyu KANG
Author Information
1. Department of Neurosurgery, National Medical Center, Seoul, Korea. chsjwa@hanmail.net
- Publication Type:Case Report
- Keywords:
Tuberculoma;
Spinal cord;
Antituberculous therapy
- MeSH:
Humans;
Paraparesis;
Spinal Cord;
Tuberculoma*
- From:Journal of Korean Neurosurgical Society
2007;41(6):408-410
- CountryRepublic of Korea
- Language:English
-
Abstract:
"Paradoxical deterioration" during antituberculous therapy is generally defined as the clinical or radiological worsening of pre-existing tuberculous lesions or the development of new lesions in a patient who initially improves. The phenomenon of paradoxical deterioration in intramedullary tuberculoma of the spinal cord is rare and is a less established entity. The authors present an unusual case of paraparesis as a result of paradoxical deterioration of intramedullary tuberculoma despite adequate antituberculous therapy. Here, we review the relevant literatures and discuss its possible pathogenic mechanisms.
