Effects of gamma-irradiation on the infectivity and chromosome aberration of Clonorchis sinensis.
- Author:
Gab Man PARK
1
;
Tai Soon YONG
Author Information
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- MeSH: Animals; Chromosome Aberrations/*radiation effects; Clonorchis sinensis/*genetics/physiology/*radiation effects; Dose-Response Relationship, Radiation; Gamma Rays/*adverse effects; Rats
- From:The Korean Journal of Parasitology 2003;41(1):41-45
- CountryRepublic of Korea
- Language:English
- Abstract: Effects of gamma irradiation on the worm survival and chromosomal aberration of Clonorchis sinensis were studied. The metacercariae irradiated with various amounts of gamma radiation (ranging from 5 Gy to 50 Gy) were fed to rats, and the effects were compared with those of non-irradiated controls. Recovery rates of adult worms in irradiated groups were reduced gradually as increasing of the irradiation doses. No worm was recovered from rats which were fed with 50 Gy irradiated metacercariae. The chromosome number was 2n = 56 in all worms from all experimental groups. However, the groups irradiated with 20 Gy, 25 Gy or 30 Gy showed variations in the chromosome number, depending on different cells in the same individual. Radiation doses used in this study did not appear to induce chromosome aberrations, however, irradiation with 30 Gy showed slightly reduced chromosome size.
