A survey on head lice infestation in Korea (2001) and the therapeutic efficacy of oral trimethoprim/sulfamethoxazole adding to lindane shampoo.
- Author:
Seobo SIM
1
;
In Yong LEE
;
Kyu Jae LEE
;
Jang Hoon SEO
;
Kyung Il IM
;
Myeong Heon SHIN
;
Tai Soon YONG
Author Information
- Publication Type:Original Article ; Clinical Trial ; Controlled Clinical Trial
- MeSH: Animals; Anti-Infective Agents/therapeutic use; Child; Drug Therapy, Combination; Female; *Hair Preparations; Health Surveys; Humans; Korea/epidemiology; Lice Infestations/*drug therapy/*epidemiology; Lindane/*therapeutic use; Male; *Pediculus; Prevalence; Students; Trimethoprim-Sulfamethoxazole Combination/*therapeutic use
- From:The Korean Journal of Parasitology 2003;41(1):57-61
- CountryRepublic of Korea
- Language:English
- Abstract: Total of 7, 495 children including 3, 908 boys and 3, 587 girls from a kindergarten and 15 primary schools were examined for head lice infestation (HLI). The overall prevalence of HLI in this study was found to be 5.8%. Head lice were much more commonly detected in girls than in boys with prevalence of 11.2% and 0.9%, respectively. Sixty-nine children with HLI were treated with 1% lindane shampoo alone (group 1), and 45 children with HLI were treated with 1% lindane shampoo and oral trimethoprim/sulfamethoxazole (group 2), and follow-up visits were conducted 2 and 4 weeks later. The children who still had HLI 2 weeks after the primary treatment were treated again. At the 2-week follow-up visit, the treatment success rates of groups 1 and 2 were 76.8% and 86.7%, respectively, and at the 4-week follow-up visit, the rates were 91.3% and 97.8%, respectively. No statistically significant synergistic effect was observed for the combination of a 1% lindane shampoo and oral trimethoprim/sulfamethoxazole.