Seroprevalence of toxoplasmosis in Korean pregnant women.
10.3347/kjp.2005.43.2.69
- Author:
Kyoung Ju SONG
;
Jong Chul SHIN
;
Ho Joon SHIN
;
Ho Woo NAM
- Publication Type:Original Article
- Keywords:
Toxoplasma gondii;
congenital toxoplasmosis;
seroprevalence;
amniotic fluid;
ELISA;
PCR
- MeSH:
Adult;
Animals;
Antibodies, Protozoan/*blood;
Female;
Humans;
Korea/epidemiology;
Pregnancy;
Pregnancy Complications/diet therapy/*epidemiology;
Seroepidemiologic Studies;
Toxoplasma/*immunology;
Toxoplasmosis/*epidemiology
- From:The Korean Journal of Parasitology
2005;43(2):69-71
- CountryRepublic of Korea
- Language:English
-
Abstract:
This study was performed in order to evaluate the sero-epidemiological status of toxoplasmosis in pregnant Korean women. Among 5, 175 sera and 750 amniotic fluid samples obtained from pregnant women, 41 serum samples (0.79%) and 10 (1.33%) amniotic fluid samples tested positive for IgG antibodies by ELISA. Fifty one cases showing a score more than 0.25 on ELISA were tested for PCR reaction against the SAG1 gene. Only one case of the 51 ELISA positive cases exhibited a positive reaction on all tests. This case had a history of acute nephropyelitis during early pregnancy, but fortunately, had delivered a phenotypically healthy baby. In this study, the seroprevalence of toxoplasmosis in pregnant women was found to be comparatively low, consistent with previous reports from Korea. However our trials, performed with a variety of diagnostic tools, were considered to be useful for the precise diagnosis of congenital toxoplasmosis.
