Guidelines for the Treatment of Functional Dyspepsia.
- Author:
Sam Ryong JEE
1
;
Hye Kyung JUNG
;
Byung Hoon MIN
;
Kee Don CHOI
;
Poong Lyul RHEE
;
Young Woo KANG
;
Sang In LEE
Author Information
- Publication Type:Review ; English Abstract ; Practice Guideline
- Keywords: Functional; Dyspepsia; Treatment; Guideline
- MeSH: Antacids/therapeutic use; Anti-Ulcer Agents/therapeutic use; Antidepressive Agents/therapeutic use; Dyspepsia/diet therapy/*therapy; Gastroscopy; Helicobacter Infections/drug therapy; Helicobacter pylori; Histamine H2 Antagonists/therapeutic use; Humans; Proton Pump Inhibitors/therapeutic use; Psychotherapy; Serotonin 5-HT3 Receptor Antagonists/therapeutic use; Vasoconstrictor Agents/therapeutic use
- From:The Korean Journal of Gastroenterology 2011;57(2):67-81
- CountryRepublic of Korea
- Language:Korean
- Abstract: Functional dyspepsia (FD) is defined as the presence of symptoms thought to originate in the gastroduodenal area, in the absence of any organic, systemic, or metabolic disease that is likely to explain the symptoms. Based on the available evidence and consensus opinion, thirteen consensus statements for the treatment of FD were developed using the modified Delphi approach. Proton pump inhibitor, prokinetics, and histamine 2 receptor antagonists are effective for the treatment of FD. Mucosal protecting agents, fundus relaxant, and drugs for visceral hypersensitivity can improve symptoms in FD. Antacids and antidepressants may help improving symptoms in FD. Comparing endoscopy with 'test and treat' of Helicobacter pylori, endoscopy may be more effective initial strategy for managing patients with FD in Korea given high incidence of gastric cancer and low cost of endoscopy. Helicobacter pylori eradication can be one of the therapeutic options for patients with FD. Psychotherapy is effective for those who have severe symptoms and refractoriness. Further studies are strongly needed to develop better treatment strategies for Korean patients with FD.
