The Influence of Miotic and Mydriatic Drugs on the Choroidal Blood Flow in Rabbits.
- Author:
Jae Myung KIM
1
;
Won Shik YOUN
Author Information
1. Department of Ophthalmology, School of Medicine, Seoul National University. SeouI, Korea.
- Publication Type:Original Article
- MeSH:
Atropine;
Calorimetry;
Choroid*;
Miotics;
Pilocarpine;
Rabbits*
- From:Journal of the Korean Ophthalmological Society
1966;7(2):47-49
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The changes in the choroidal blood flow induced by the intravenously administered miotics (pilocarpine, 1mg/kg) and mydriatics(atropine, O.1mg/kg) were investigated in rabbits with the use of the blood flow measuring apparatus according to the principle of Grayson's internal calorimetry, thermistors as sensing elements. Atropine caused slow increase in the choroidal blood flow after transient decrease, the maximal increase being about 85% of the pre-injection level. Pilocarpine also produced moderate increase of the blood flow by more than 100% of the original level. From these data it is concluded that both atropine and pilocarpine caused significant increase in the choroidal blood flow in rabbit.
