A Case Report Of Castleman's Disease On Oral And Maxillofacial Region.
- Author:
In Kyo CHUNG
1
;
Uk Kyu KIM
;
Sang Hoon SHIN
;
Hye Ryun PARK
;
Eui Hoon LEE
;
Won Seok JANG
Author Information
1. Department of Oral and Maxillofacial surgery, College of Dentistry, Pusan National University,Korea. E-mail: inkchung@hyowon.cc.pusan.ac.kr
- Publication Type:Case Report
- Keywords:
Castleman's disease
- MeSH:
Abdomen;
Angiofibroma;
Antineoplastic Agents;
Diagnosis;
Female;
Giant Lymph Node Hyperplasia*;
Humans;
Lymph Nodes;
Lymphoma;
Lymphoproliferative Disorders;
Radiotherapy;
Sarcoma, Kaposi;
Steroids;
Thorax
- From:Journal of the Korean Association of Oral and Maxillofacial Surgeons
2001;27(5):468-473
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Castleman's disease or angiofollicular lymph node hyperplasia, is a rare lymphoproliferative disorder. It may be appear as a local or generalized tumor-like condition, usually in chest or abdomen and may involve both lymph nodes and non-nodal tissues. Castleman's disease is an unusal entity which may at times mimic malignancy but is entirely benign in nature. It is topical as it has been noted to occur with AIDS and Kaposi's sarcoma. Careful interpretation of radiogram may help to distinguish Castleman's disease from other tumor condition, such as lymphoma, neurogenic tumor, or even angiofibroma, etc. But exact diagnosis must be made on the basis of histologic confirmation. In addition to histologic features, clinical distinction between the localized and multicentric form is important in selecting appropriate management. Surgical excision of an localized mass is the first choice of treatment. Partial resection, radiotherapy or observation alone may avoid the need for exessively aggressive therapy. Patients with multicentric disease don't benefit by surgical management because of systemic manifestation and rapid deterioration. Thus, antineoplastic agents and steroids may offer an alternative form of therapy. We report a case of female patient with Castleman's disease in oral and maxillofacial region, treated by surgical excision with good results.
