A Case of Congenital Melanocytic Nevus Undergoing Regression in Association with Vitiligo.
- Author:
Hye Jeong CHOI
1
;
Ja Kyung KU
;
Young Min PARK
;
Hyung Ok KIM
Author Information
1. Department of Dermatology, Kangnam St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. knderma@cmc.cuk.ac.kr
- Publication Type:Case Report
- Keywords:
Congenital melanocytic nevus;
Vitiligo;
Regression;
Apoptosis
- MeSH:
Male;
Humans
- From:Korean Journal of Dermatology
2004;42(1):65-68
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Congenital melanocytic nevi rarely develop depigmentation, and only a few cases have been reported in the literature. We, herein, present a case of congenital melanocytic nevus which has undergone progressive involution in association with vitiligo. A 23-year-old man had a dark brownish patch partially surrounded by the depigmented patch on his mid back. He also had multiple depigmented patches on his trunk and neck, which had developed since the age of 5. Histopathologic examination from the dark brownish patch adjacent to the depigmented area showed typical findings of compound nevus with a mild perivascular lymphocytic infiltration. TUNEL staining from the same lesion demonstrated many strong positive epidermal basal cells as well as dermal nevus cells, indicative of apoptosis.
