An MRI Study of Cavum Septi Pellucidi in Schizophrenia and Mood Disorder.
- Author:
Sang Eun SHIN
1
;
Min Hee KANG
;
Churl Eung KIM
;
Jeong Seop LEE
;
Jae Nam BAE
Author Information
1. Department of Psychiatry, College of Medicine, Inha University, Inchon.
- Publication Type:Original Article
- Keywords:
Cavum septi pellucidi;
Schizophrenia;
Mood disorder
- MeSH:
Brain;
Carum;
Humans;
Incidence;
Magnetic Resonance Imaging*;
Mood Disorders*;
Schizophrenia*
- From:Journal of Korean Neuropsychiatric Association
2000;39(4):720-728
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: This study was designed to verify neuro-developmental hypothesis of schizophrenia and mood disorder. METHOD: We performed Brain Magnetic Resonance Imaging study in 34 schizophrenic patients, 18 mood disorder patients and 22 controls and compared the incidence and the size of carum septi pellucidi (CSP). RESULTS: The incidences of CSP in schizophrenia, mood disorder and controls were 61%, 61%, and 41%, respectively. The incidences of large CSP, defined as largest diameter larger than 3mm in T1-weighted image, were 24% in schizophrenic patients, 11% in mood disorder patients, and 5% in controls. But they didn't show statistically significant differences. CONCLUSION: We could find the tendency that the incidence of CSP was high as following order; schizophrenia, mood disorder, controls. But it was not statistically significant difference. To verify neuro-developmental hypothesis, we need larger pool of patients and better study design.
