A Case of Pancreatic Endocrine and Exocrine Tumor with MEN Type I.
- Author:
Oh Wan KWON
1
;
Ho Soon CHOI
;
Jee Hyun KIM
;
Won MOON
;
Jung Mi KIM
;
Dong Hee KOH
;
Hang Rak LEE
;
Oh Young LEE
;
Byung Chul YOUN
;
Joon Soo HAM
;
Dong Hoo LEE
;
Min Ho LEE
;
Choon Suhk KEE
Author Information
1. Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea. choihs@hanyang.ac.kr
- Publication Type:Case Report
- Keywords:
Carcinoma;
Acinar cell;
Islet tumor;
Hemosuccus pancreaticus;
MEN type I
- MeSH:
Abdominal Pain;
Acinar Cells;
Carcinoma, Acinar Cell;
Female;
Head;
Humans;
Hyperparathyroidism;
Incidence;
Male;
Melena;
Middle Aged;
Multiple Endocrine Neoplasia Type 1;
Pancreas;
Pancreas, Exocrine;
Parathyroid Neoplasms
- From:Korean Journal of Gastrointestinal Endoscopy
2006;33(5):326-332
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
An acinar cell carcinoma of the exocrine pancreas is a rare tumor with reported a incidence of 1% to 2% of pancreatic carcinomas. Cases of acinar cell carcinomas with amphicrine features have been reported in recent decades. However, there are no reports of two simultaneous pancreatic masses: an endocrine tumor and, an exocrine tumor. We encountered a 59-year-old female patient presenting with abdominal pain and melena. The acinar cell carcinoma was a 1x1 cm-sized round solid mass in the head of the pancreas. The islet tumor was a 2.5x1.5 cm-sized round mass in the body of the pancreas. The endocrine tumor was nonfunctioning. Melena resulted from the hemosuccus pancreaticus due to a ductal invasion of the acinar cell carcinoma. The patient had a parathyroid adenoma with hyperparathyroidism. Therefore, both the islet tumor and parathyroid adenoma with hyperparathyroidism were strongly suggestive of a MEN I.
