A Case of Neuronal Heterotopia.
- Author:
Jeong Hae JOO
1
;
Eun Joo SEOK
;
Min Jeong KIM
;
Son Sang SEO
Author Information
1. Department of Pediatrics, Il Sin Christian Hospital, Pusan, Korea.
- Publication Type:Case Report
- Keywords:
Neuronal heterotopia;
Agenesis of corpus callosum;
Neuronal migration disorders
- MeSH:
Agenesis of Corpus Callosum;
Brain;
Lissencephaly;
Malformations of Cortical Development;
Neocortex;
Neuronal Migration Disorders;
Neurons*
- From:Journal of the Korean Pediatric Society
1997;40(8):1173-1177
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Neuronal migrational disorders of the brain represent abnormalities in the formation of the neocortex caused by faulty migration of the subependymal neuroblasts. The neuroblasts normally migrate between the sixth and 15th gestational week and in doing so form the six-layered neocortex. When the migration does not occur in a normal fashion the resultant brain anomalies include lissencephaly, pachygyria, schizencephaly, hemimegalencephaly, heterotopia, and polymicrogyria. Neuronal heterotopia is a collection of nerve cells in abnormal locations as a result of arrest of their radial migration, improper formation, or destruction of the radial glial fiber. We reported a case of neuronal heterotopia with brief review of related literatures.