The Cardiovascular Effects of Vecuronium during Anesthesia with Isoflurane.
10.4097/kjae.1989.22.4.482
- Author:
Jung Seok LEE
1
;
Hae Kyu KIM
;
Inn Se KIM
;
Kyoo Sub CHUNG
Author Information
1. Department of Anesthesiology, College of Medicine, Pusan National University, Pusan, Korea.
- Publication Type:Original Article
- Keywords:
Cardiovascular effects;
Vecuronium;
Pancuronium;
Isoflurane
- MeSH:
Anesthesia*;
Animals;
Arterial Pressure;
Cardiac Output;
Dogs;
Heart Rate;
Isoflurane*;
Oxygen;
Pancuronium;
Thiopental;
Vecuronium Bromide*
- From:Korean Journal of Anesthesiology
1989;22(4):482-487
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
To investigate the cardiovascular effects of vecuronium during isoflurane anesthesia, I compared with effects of pancuronium. Eight mongrel dogs were anesthetized with intravenous thiopental sodium and maintained with oxygen (41/min)-isoflurane (1 MAC). Cardiovascular parameters were determined and recorded 1 minute before and 5, 10, 20, 30 minutes after administration of 3 times the ED, dose of pancuronium and vecuronium respectively. Only one neuromuscular relaxant was studied with each anesthetic administration. The results are as follows; 1) Pancuronium increased heart rate, mean arterial blood pressure, cardiac output. 2) Vecuronium caused no significant cardiovascular chanaes.
