A Case of Idiopathic Hypereosinophilic Syndrome with Hepatic Involvement in a 5-Year-Old Boy.
- Author:
Young Mi KIM
1
;
Yoon Jin LEE
;
Jae Hong PARK
;
Jun Woo LEE
;
Chang Hun LEE
Author Information
1. Department of Pediatrics, College of Medicine, Pusan National University, Pusan, Korea. jhongpark@pusan.ac.kr
- Publication Type:Case Report ; English Abstract
- Keywords:
Idiopathic hypereosinophilic syndrome;
Hepatic involvement
- MeSH:
Child, Preschool;
English Abstract;
Eosinophils/pathology;
Human;
Hypereosinophilic Syndrome/*complications/diagnosis;
Liver/pathology;
Liver Diseases/*complications/diagnosis/pathology;
Male
- From:The Korean Journal of Hepatology
2002;8(3):321-326
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Idiopathic hypereosinophilic syndrome is defined as the presence of prolonged eosinophilia without an identifiable underlying cause and with evidence of end-organ dysfunction. The organs involved are the heart, bone marrow, nervous system, lungs, liver, skin, and gastrointestinal tract. Hepatic involvement is found in about 30% of patients of idiopathic hypereosinophilic syndrome. It occurs rarely in infants and children. In this report, we experienced one case of idiopathic hypereosinophilic syndrome with hepatic involvement in a 5-year-old boy who complained of intermittent fever and right upper quadrant abdominal pain. An abdominal ultrasound examination revealed an ill-defined low-echoic lesion in the liver. Pathologic findings of a biopsy specimen clearly showed the infiltration of eosinophils in the liver. Laboratory data disclosed absolute eosinophilia. There was no evidence of allergic disease or parasitic infestation.
